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Comparative efficacy of continuous versus intermittent administration of furosemide in acute heart failure: an updated systematic review and meta-analysis of 22 RCTs.

Front Cardiovasc Med · 2026 · PMC13333736 · PMID 42440860

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a numerical trendno p-value reported
The intermittent intravenous (iIV) arm showed a numerical trend toward all-cause mortality without reaching statistical significance (low evidence quality) compared with the continuous intravenous (cIV) arm (RR: 1.36, 95% CI: 0.96–1.94, p = 0.08).

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