Diagnostic Utility of Serum Sodium Compared With C-reactive Protein and Total Leukocyte Count for Predicting Appendiceal Perforation and Clinical Outcomes in Adult Patients With Acute Appendicitis: A Prospective Observational Study.

Cureus · 2026 · PMC13334759 · PMID 42440993

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hedged sentence

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highly significantno p-value reported

Hyponatremia (<135 mEq/L) showed a highly significant association with appendiceal perforation.

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