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NAD<sup>+</sup> Metabolism Licenses Zygotic Genome Activation via PARP7-Mediated ADP-Ribosylation of UHRF1 in Mouse Early Embryos.

Adv Sci (Weinh) · 2026 · PMC13336359 · PMID 42294794

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a decreasing trendno p-value reported
In PARP7i late‐2Cell embryos, 193 major ZGA genes (17% of the set) showed insufficient expression, displaying a decreasing trend (Figure 4H ).

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