Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation.

Although this effect persisted post‐EPS for both NMJs > 2 μm and larger NMJs > 5 μm, it was not as significant on day 60.

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Strikingly, one month of EPS‐training, applied under stable or increasing parameters, induced a highly significant increase in the absolute number, size, and innervation of mature NMJ‐like structures (>5 μm) on day 60 compared to non‐paced control NMOs (Figure 2c,d ).

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