Rhein ameliorates MASH via EGFR/AKT/PPARα-mediated coordinated regulation of metabolism and inflammation.

Front Pharmacol · 2026 · PMC13337408 · PMID 42416832

Europe PMC DOI

hedged sentence

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

a trend toward significancep = 0.07so close (0.05 < p ≤ 0.1)

Notably, EGFR knockdown alone (sh Egfr group) resulted in a liver-to-body weight ratio that was higher than that of the model group, showing a trend toward significance (p = 0.07) ( Figure 7C ).

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