a slight trendP = 0.198
The therapeutic effect did not significantly differ across follow-up visits but showed a slight trend of diminishing over time (HFS: F (1.6, 15.55) = 1.82, P = 0.198; VFS: F (1.7, 17.37) = 1.44, P = 0.263; LFS: F (3, 30) = 0.86, P = 0.475).