highly significantp = 0.0001
The CT heterozygote once more demonstrated a significantly lower risk (OR = 0.36; 95% CI = 0.2–0.5; p = 0.0001) among individuals without a family history, while the TT homozygous mutant genotype demonstrated a highly significant increased risk (OR = 2.79; 95% CI = 1.7–4.3; p = 0.0001).