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Elevated Circulating HMGB1 Levels as a Potential Biomarker for the Diagnosis and Therapy of Heart Failure: A Cross-Sectional Study.

Rev Cardiovasc Med · 2026 · PMC13339188 · PMID 42416580

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an increasing trendno p-value reported
The results of the latest epidemiological survey in China indicate that the total number of prevalent cases of heart failure increased from 7.03 million in 1990 to 18.51 million in 2019, showing an increasing trend year by year, with a prevalence rate of 1.3% among residents aged 35 and older [ 4 , 5 ].

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