Effect of inactivation of the USP19 deubiquitinase gene in mice on important phenotypes of aging.

J Gerontol A Biol Sci Med Sci · 2026 · PMC13341015 · PMID 42225593

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a small trendno p-value reported

Female KO mice had significantly increased O 2 consumption and CO 2 production compared to WT mice ( Figure 3H and I ), while there was only a small trend toward increases in the male KO mice ( Figure 3C and D ).

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a slight trendno p-value reported

The male KO mice showed a slight trend toward a decreased RER ( Figure 3E ), suggesting oxidation of more fat in the KO mice.

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