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ZBTB7A-mediated regulation of astrocytic glycolysis in neurodegenerative diseases: insights from literature review and bioinformatics prediction.

Front Aging Neurosci · 2026 · PMC13342185 · PMID 42422112

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In the brains of patients with AD, significant increases in the expression levels of glycolytic enzymes were observed with a decreasing trend in oxygen consumption, which directly led to increases in glucose uptake and lactate production ( Bigl et al., 1999 ; Tang, 2020 ; Preeti et al., 2022 ).

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