Studies suggest that lipophilic drugs are most commonly incorporated into liposomes using the thin-film hydration method 23 , 33 ; the thin film hydration method remains highly significant in preclinical, and translational pharmaceutical settings despite the availability of advanced techniques such as microfluidics, ethanol injection, reverse-phase evaporation, or high-pressure homogenization .
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PEGylated liposomes enhance the pharmacokinetics, biodistribution, anticancer efficacy, and safety of Kaempferol, a phytomolecule enrolled in clinical trials.
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