ARID3A knockdown facilitates ferroptosis partly through modulation of the PTEN/Akt pathway in breast cancer.

Oncol Lett · 2026 · PMC13343340 · PMID 42422225

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an increasing trendno p-value reported

ARID3A knockdown upregulates PTEN expression and inactivates the Akt pathway in breast cancer cell lines siARID3A transfection significantly upregulated PTEN expression in MCF-7 cells, while PTEN expression exhibited an increasing trend but did not reach statistical significance in MDA-MB-231 cells.

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