TRPC6 Inhibition Attenuates Renal Tubulointerstitial Fibrosis via the Reactive Oxygen Species/TXNIP/NLRP3 Signaling Pathway.

Kidney Blood Press Res · 2026 · PMC13345608 · PMID 42030211

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a slight trendno p-value reported

Third, co-treatment with SAR7334 and MCC950 in vitro showed a slight trend toward further reduction of fibrosis-related and NLRP3 pathway markers, but the difference did not reach statistical significance.

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