Impact of Frailty and Diaphragmatic Dysfunction on Outcomes in ARDS: Focusing on Perioperative Respiratory Management.

Clin Respir J · 2026 · PMC13345777 · PMID 42420198

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.1980

boldest claim

The sentences

highly significantp < 0.001actually significant

The interaction term for frailty and the diaphragm was highly significant (OR = 4.23, 95% CI: 2.37–7.54, p < 0.001), which further demonstrated supra‐additive synergy confirmed by additive interaction metrics (RERI = 1.94, AP = 0.46, SI = 2.31; all p < 0.05).

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a nonsignificant trendp = 0.198not close (p > 0.1)

After IPTW adjustment, the IMT‐treated frail patients had a 3.1‐day (95% CI: 0.4–5.8, p = 0.024) reduction in mechanical ventilation duration with a nonsignificant trend toward lower 28‐day mortality ( p = 0.198).

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