There is a highly significant inverse correlation between the abundance of PTEN and miR-22 [ 180 ]. miR-214 is upregulated following T cell activation, coinciding with a substantial reduction in PTEN mRNA in both CD4 + and CD8 + T cells [ 181 ].
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The cross-talk between GSK-3β, RKIP, and PTEN as potential targets for therapeutic implications in cancer: a comprehensive insight.
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