VCP modulation ameliorates pathological features in C9orf72 models.

Cell Death Dis · 2026 · PMC13346533 · PMID 42143042

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highly significantno p-value reported

2D , we found an increase in lysosomal size in cells expressing the C9-DPRs, which was highly significant for polyGA, polyGP, and polyPA (Fig. 2D ).

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a positive trendno p-value reported

A positive trend was also visible in LHX4 expression levels.

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