Fluoxetine Use for Very Young Children with Major Depression Disorder: A Pilot Randomized Clinical Trial.

Based on the reports of the Global Burden of Disease Guidelines, it is estimated that depression would become the second by the end of 2020.[ 1 ] Despite all the efforts made to prevent MDD or diagnose it in its early stages, further investigations in 2024 have revealed that an increasing trend of MDD development is going on.[ 2 , 3 ] Moreover, depression negatively impacts public health with a greater impact than physical disorders such as coronary heart disease.[ 4 ] Depression diagnosis was made using the last version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V)

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