Antagonism of β-klotho signaling by peptide 19 impairs wheel running in male mice and potentiates the cisplatin-induced decrease in wheel running.

Front Pharmacol · 2026 · PMC13350045 · PMID 42434120

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highly significantp < 0.01actually significant

This was confirmed by an ANOVA conducted on days 1–5, which showed a highly significant effect of peptide 19 (F(1, 28) = 11.0, p < 0.01) ( Figure 4 ).

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