Effectiveness of vericiguat in heart failure across ejection fraction phenotypes: a comprehensive meta-analytic trial sequential analysis and meta-regression analysis.

Ann Med Surg (Lond) · 2026 · PMC13354362 · PMID 42433820

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hedged sentence

0.1440

closest p · 2.9× alpha

0.1440

boldest claim

The sentences

a trend toward significanceP = 0.144not close (p > 0.1)

Model 3, focusing on age and NT-proBNP with an interaction term, reported a non-significant intercept of −28.6551 ( P = 0.1584, 95% CI: −68.4712 to 11.1609), with age showing a trend toward significance (estimate: 0.4224, P = 0.144, 95% CI: −0.1443 to 0.9892).

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