Efficacy and safety of obicetrapib in patients at high cardiovascular risk: a systematic review, meta-analysis, and meta-regression.

Ann Med Surg (Lond) · 2026 · PMC13354417 · PMID 42433756

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hedged sentence

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

highly significantP < 0.00001actually significant

The pooled MD was −20.25 (95% CI: −23.25 to −17.25), favoring obicetrapib, with a highly significant overall effect ( Z = 13.24, P < 0.00001).

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