"Point education" and "rotation communication" on antimicrobial policy implementation: an interrupted time series analysis of declining cephalosporin skin test rates.

Second Nephrology Ward (direct intervention group): A highly significant immediate reduction in CST rate (-71.081%, P < 0.001) and a significant sustained declining trend (slope: -0.121, P < 0.001) (Table 4 ; Fig. 2 B).

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Analysis of treatment adjustments reveals a notable trend of quinolone use after positive CST, continued risk aversion among prescribers but could potentially contribute to unnecessary broader-spectrum antibiotic use and antimicrobial resistance [ 25 ].

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