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Cancer-Associated Fibroblast-Targeted Nanomedicine in Solid Tumor Therapy: From Mechanisms of Therapeutic Resistance to Precision Stromal Modulation.

Int J Nanomedicine · 2026 · PMC13355663 · PMID 42437015

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a favorable trendno p-value reported
8.5 months, suggesting a favorable trend. 286 These results indicate that stroma-directed therapies may require biomarker-based patient selection, and that patients with high hyaluronan levels are more likely to experience clinical benefit from improved drug delivery.

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