CD31<sup>+</sup> Cell Enrichment Enhances Therapeutic Effects of Stromal Vascular Fraction in Experimental Primary Osteoarthritis: A Preclinical Study in the Dunkin Hartley Guinea Pig Model.

Conversely, trabecular thickness (Tb.Th), which increases in OA‐associated remodeling, showed a decreasing trend in both treatment groups compared to the DPBS group, with a significant difference detected between DPBS and SVF groups ( p = 0.033), suggesting that Tb.Th may also be regulated by SVF and CD31 + SVF (Figure 10C ).

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In the SVF group, a significant improvement was observed in osteophyte formation ( p = 0.014), while cartilage structure ( p = 0.066) and total histological scores ( p = 0.062) showed a trend toward significance.

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