Dental anomalies and dental age in children with down syndrome: a comparative retrospective study with healthy controls.

BMC Oral Health · 2026 · PMC13356790 · PMID 42163284

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highly significantno p-value reported

In their validation of the Nolla method, they found that the 8–8.9 age group exhibited highly significant discrepancies between chronological and dental, indicating that this specific window is particularly sensitive to maturation lags [ 32 ].

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