Barely Significant
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Adaptive Evolution of Serotype O Foot-and-Mouth Disease Virus Under Vaccine Pressure: Combined VP1 T142/Q153 Mutations Drive Antigenic Alteration and Immune Evasion.

Transbound Emerg Dis · 2026 · PMC13358367 · PMID 42438383

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The sentences

extremely significantp < 0.0001actually significant
On Day 42 after immunization, the antibody titer of the 3D‐LS‐LOOP (T142P&Q153P) group was 1:2 7.67 , ~10 times higher than that of the 3D‐LS‐LOOP (Wt) group (1:2 4.33 ), presenting an extremely significant difference between groups ( p < 0.0001).

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