Barely Significant
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Brain-targeting lipid nanoparticles of nicotinamide mononucleotide: preparation, optimization, and characterization.

Front Chem · 2026 · PMC13358926 · PMID 42444846

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highly significantP < 0.0001actually significant
The regression equation between the independent and dependent variables was derived from the fitting process: Y = 29.52 + 0.9 A + 0.6375 B ‐ 1.24 C + 0.675 AB ‐ 0.375 AC ‐ 0.3 BC ‐ 1.76 A 2 ‐ 1.54 B 2 ‐ 2.33 C 2 R 2 = 0.994 The regression model for EE was highly significant ( P < 0.0001), while the lack-of-fit term was non-significant ( P = 0.6507), indicating good model adequacy.

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