The Live-Attenuated PruΔ<i>gra47</i> Strain of <i>Toxoplasma gondii</i> Confers Protective Immunity Against Acute and Chronic Toxoplasmosis in Mice.

For the PYS strain (low virulence relative to the RH strain), immunized mice were completely protected (100% survival) against challenge with both doses, whereas naive controls exhibited high mortality, with statistically significant differences at 10 2 PYS tachyzoites ( Figure 5 a) and highly significant differences at 10 3 PYS tachyzoites ( Figure 5 b).

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