Ranking of antiseizure medications in a panel of focal seizure models predicts their comparative efficacy in clinical add-on trials in drug-resistant focal epilepsy.

Epilepsia · 2026 · PMC13360943 · PMID 41902701

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highly significantno p-value reported

However, when we combined the ED 50 ‐based ranks from two to four models of focal‐onset seizures, highly significant positive correlations with seizure‐freedom rates in the clinical trials were obtained.

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