First Insights on the Upcoming Role of Next-Generation PLLA-LASYNPRO in Aesthetic and Regenerative Medicine: A Survey of Experts-the PLLA-LASYNPRO Rationale.

A recent Spanish interim multicenter analysis of 36 adult subjects confirmed the safety and rejuvenating efficacy of the PLLA-LASYNPRO microsphere implants on mild to severe nasolabial folds. 17 Assessed with two photo-numeric tools, the five-grade Wrinkle Severity Rating Scale (WSRS) and the six-point Midface Volume Deficit Scale (MFVDS) focused on middle third facial volume loss, 44.4 and 63.9% of subjects reported highly significant score improvements 1 and 2 months, respectively, after the first injection. 18 Wrinkle improvements were at least 1 point compared to baseline and uniform on the right and left facial sides.

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