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Albumin administration and 28-day mortality in sepsis-induced myocardial injury: a propensity score-matched analysis.

Front Pharmacol · 2026 · PMC13365149 · PMID 42453584

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a numerical trendno p-value reported
In the severe hypoalbuminemia cohort (baseline serum albumin ≤2.8 g/dL), a numerical trend toward improved survival was observed with albumin supplementation; however, this effect did not attain statistical significance(HR 0.80, 95%CI 0.41–1.58) ( Figure 3 ). 5 Discussion In the propensity score-matched cohort of SIMI patients with comparable baseline albumin levels (mean 2.8 g/dL in both groups; p = 0.142), albumin administration demonstrated no mortality benefit across all evaluated endpoints: 28-day, 60-day, and 90-day mortality, as well as in-hospital mortality.

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