SHIELD: A weakly supervised graph attention neural network for decoding disease-relevant cell-cell interactions.

Patterns (N Y) · 2026 · PMC13366524 · PMID 42453692

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highly significantno p-value reported

These interactions were highly significant according to false discovery rate (FDR)-corrected Mann-Whitney U tests and occurred in the top-left quadrant of the NN control plot—indicating for the rim ROI that although these interactions are spatially rare, SHIELD assigns them high biological relevance.

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