From linear model analysis, the interaction between sex and E2 treatment was highly significant, indicating that sex significantly impacts the response of these cells to E2 supplementation in a manner beyond which is explained simply by the sex differences alone.
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Media matters: phenol red and fetal bovine serum estrogen in traditional cell culture media influence human mesenchymal stromal cell (hMSC) processes and differentiation in a sex-biased manner.
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