Optimized Lipid Nanoparticles with Tail-Modified Ionizable Lipids for Safer mRNA Delivery.

Adv Sci (Weinh) · 2026 · PMC13367110 · PMID 42446186

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a nonsignificant trendno p-value reported

However, TM2 elicited lower IFN‐γ responses compared to the ORI, and TM1, with a nonsignificant trend toward lower responses relative to TM3.

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