Multilayer Proteome and Metabolome-Based Validation Uncovers Combined Regulatory Roles and Predictive Values of 6 RNA Modifications and Cellular Senescence in Alzheimer's Disease.

CNS Neurosci Ther · 2026 · PMC13367321 · PMID 42446473

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an overall trendno p-value reported

Differential abundance (DA) analysis was employed to evaluate the average values and overall changes of metabolites involved in corresponding metabolic pathways, which depicted that metabolic pathways, including D‐amino acid metabolism, exhibited an overall trend of upregulation (Figure 6C ).

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