Modular <i>in vitro</i> evaluation of buparlisib-polymeric nanomedicines in 2D and 3D models of glioblastoma.

Increasing the concentration to 200 μM led to a moderate decrease in metabolic activity in U87MG cells and approximately 50% reduction in U118MG (borderline insignificant inhibition compared to control; p_adj = 0.0509; Supplementary Table S1b ) and T98G cells (borderline significant inhibition compared to control, p_adj = 0.0477, depicted in Figure 2C as hatched bar; Supplementary Table S1b ).

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