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Chromatic differential confocal matrix-based 3D topography and hyperspectral imaging with deep learning for osteoarthritis grading.

Biomed Opt Express · 2026 · PMC13372382 · PMID 42460347

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an overall trendno p-value reported
From an overall trend perspective, as the degeneration grade progresses from Grade I to Grade III, the spectral curves exhibit a distinct “red shift": relative to the long-wavelength band (620 nm), the reflectance intensity in the short-wavelength band (430–500 nm) decreases progressively.

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