Circulating microRNAs reveal egg-brain crosstalk and a brain-predominant microRNA linked to the onset of the next reproductive cycle in iteroparous salmonids.

BMC Biol · 2026 · PMC13374286 · PMID 42168984

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

highly significantno p-value reported

When eggs are removed from the body cavity upon ovulation, we observed a dramatic and highly significant downregulation of a single c-miRNA (miR-139-5p) in blood plasma (Fig. 4 C), while all other detected c-miRNAs remain unaffected.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.