Global burden and trends of non-communicable diseases among children and adolescents from 1990 to 2021: an age-period-cohort and frontier analysis with projections to 2035.

Front Public Health · 2026 · PMC13376241 · PMID 42491115

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During the same period, the global age-standardized incidence rate (ASIR) exhibited an increasing trend (AAPC = 0.05%, 95% CI: 0.03–0.07, P < 0.001), reaching 150,291.52 per 100,000 in 2021 ( Table 2 , Figure 1B ).

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