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Microglial Ccl4-Ccr5 signaling links systemic inflammation to synaptic loss and memory deficits in chronic kidney disease.

J Neuroinflammation · 2026 · PMC13377755 · PMID 42178562

Europe PMCDOI
1
hedged sentence
0.0569
closest p · 1.1× alpha
0.0569
boldest claim

The sentences

an increasing trendP = 0.0569so close (0.05 < p ≤ 0.1)
Consistent with renal dysfunction, CKD rats exhibited significantly increased blood urea nitrogen levels and urinary albumin-to-creatinine ratios, with urinary creatinine showing an increasing trend that did not reach statistical significance ( P = 0.0569) (Figure S1C).

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