Phospholipid flippases ATP8A1 and ATP8A2 regulate GABA<sub>A</sub> receptor trafficking through distinct mechanisms in hippocampal neurons.

23 Although the mechanism of these changes remains unsolved, we reasoned that, if such global changes in phospholipids were also observed in the brain of ATP8A1/ATP8A2 DKO mice, this would be highly significant and would require further investigation and discussion beyond PS exposure alone.

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