In addition, other transmembrane regions (such as S1, S2 and S3) may also contain a small amount of positively charged amino acid residues, but the positive charge density is relatively low and the sensitivity to voltage change is not as significant as that of S4 region.
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New insights into the physiological, pathological and pharmacological roles of voltage‑gated potassium channel Kv10.1 in cancer (Review).
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