SAFE: a Mix-and-Read Assay for miRNA Detection in Extracellular Vesicles From Unprocessed Plasma Toward Clinical Disease Diagnosis.

Statistical analysis revealed that signal differences between Lipo‐21 and Lipo‐R were not significant at 10 0 particles/mL (noting that this nominal concentration does not literally correspond to a single vesicle per mL due to inherent variability in NTA‐based quantification), but became significant at 10 2 particles/mL ( ** p < 0.01) and highly significant at higher EV concentrations ( **** p < 0.0001).

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