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Optimal patient selection beyond the current selection criteria for liver transplantation for unresectable colorectal liver metastasis.

Surg Today · 2026 · PMC13379493 · PMID 42032131

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an increasing trendno p-value reported
Although no study has investigated the impact of changes in CEA levels during pretransplant chemotherapy on survival, the International Hepato-Pancreato-Biliary Association consensus guidelines recommend that high CEA levels (> 80 μg/L) with an increasing trend during chemotherapy should be considered as a strong relative contraindication for LT [ 29 ].

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