Isoflavones impair anti-PD1 efficacy in breast cancer, regardless of dietary fiber or fecal short-chain fatty acid levels.

Front Immunol · 2026 · PMC13381617 · PMID 42519328

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highly significantno p-value reported

Thus, although TAM on its own promoted tumor growth in the high-MACi group, in combination with anti-PD1, it induced highly significant tumor growth reduction.

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