Electrochemically-induced regioselective cyclization of <i>N</i>-methacryloyl hydrazones: efficient synthesis of phosphorylated pyrazolone derivatives.

Introduction Pyrazolones represent an important class of N-containing heterocycles that are ubiquitously distributed in biological systems and exhibit diverse physiological and pharmacological activities, rendering them highly significant for scientific investigation. 1 In particular, 2-pyrazolin-5-ones, as an important type of pyrazolones, have potent biological activities, including neuroprotection, antitumor effects, and pancreatic lipase inhibition 2 (see Scheme 1A ).

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