Pyrazole-Derived Antibacterial Compounds Effectively Treat Methicillin-Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase.

Adv Sci (Weinh) · 2026 · PMC13383702 · PMID 42474094

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an increasing trendno p-value reported

Subsequently, the concentration of proteins in the bacterial extracellular content showed an increasing trend after treatment with different concentrations of Py‐27 (4 × MIC, 2 × MIC, and MIC), confirming the loss of cell membrane integrity (Figure 9D ).

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