Inhibition of Cathepsin C attenuates osteoarthritis by modulating macrophage activated status and reducing tissue inflammatory responses.

Bone Joint Res · 2026 · PMC13384741 · PMID 42476565

Europe PMC DOI

hedged sentence

0.2840

closest p · 5.7× alpha

0.2840

boldest claim

The sentences

a decreasing trendp = 0.284not close (p > 0.1)

While MMP13 mRNA showed a decreasing trend ( p = 0.284, one-way ANOVA with Tukey’s HSD post hoc test), its protein levels remained unchanged ( Figure 4f ).

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