Barely Significant
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Predictive value of Ki-67 expression in predicting pathological response to neoadjuvant chemotherapy combined with immunotherapy in lung squamous cell carcinoma.

Front Oncol · 2026 · PMC13384871 · PMID 42482760

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highly significantP < 0.001actually significant
Importantly, our multivariate analysis already adjusted for all major clinicopathological confounders (age, gender, smoking status, clinical stage, PD-L1), and the association between Ki-67 and MPR/pCR remained highly significant (adjusted OR per 1% increase = 1.069, P < 0.001), suggesting that the observed predictive value is robust against measured confounding.

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