Inhibition of p300/CREBBP catalytic activity drives context-dependent transcriptional activation in AML.

Blood · 2026 · PMC13386094 · PMID 41849237

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highly significantno p-value reported

Other highly significant acetylation targets were RUNX family transcription factor 1 (RUNX1), MEF2D, TRIM33, TRIM28, NONO, lysine methyltransferase 2C (KMT2C), IRF2BP2, ARID1A, and SMARCA4 ( Figure 3 D; supplemental Tables 9 and 10 ).

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