CD49d governs immune synapse formation through actin rearrangements and synchronizes BCR signaling in CLL.

Blood · 2026 · PMC13386099 · PMID 41790574

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a nonsignificant trendno p-value reported

Leukemia development was monitored monthly by analyzing CD5 + CD19 + cells in the PB of CD49dΔB TCL1-tg mice and TCL1-tg littermates, with a nonsignificant trend of higher leukocytosis at months 5, 6, 9, and 10 in the CD49dΔB TCL1-tg model ( Figure 1 B).

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